The demand for biopharmaceutical products is increasing day by day. The advancements in discovery science have led to a significant increment in the development of these products.
However, the increase in product number comes with a greater responsibility to kick the low-quality and poor drug option out of the market. This is necessary to keep the life-threatening and hazardous risks at bay. For evaluating these therapeutic entities during the developmental procedure, non-clinical testing or Bioanalysis is performed.
Bioanalysis is an analytical technique for the quantitative measuring of drugs, metabolites, macromolecules, proteins, DNA and other biological molecules in a biological system. This analysis is necessary for determining the pharmacokinetics, bioequivalence, exposure-response, and toxicokinetics of the drugs. Moreover, it helps in forensic examination and determining environmental concerns associated with the drug.
There are certain CROs that provide pharmaceutical companies with Bioanalytical laboratory services. These contract research organizations employ various techniques for Bioanalysis of the drugs and biomolecules. Common techniques used for the analysis include,
- Liquid chromatography-mass spectrometry (LC-MS)
- Gas chromatography-mass spectrometry (GC-MS)
- High performance liquid chromatography (HPLC)
- Enzyme-linked immunosorbent assay (ELISA)
- Nuclear magnetic resonance (NMR)
LC-MS is commonly used for small molecules and ELISA is popular for bioanalysis of macromolecules.
How do Bioanalytical services help to meet the present day challenges?
Pharmaceutical companies find Bioanalytical labs very helpful in moving the quality drugs into clinical development quickly. The selection process and analytical screening of these drugs provide greater success rate in the market. At present, the pharmaceutical industry bears a lot of pressure regarding developing quality and cost-effective drugs. The Bioanalytical labs serve as a supporting service to optimize the speed and success of drug development. They work to measure an active drug in a biological matrix quantitatively. This helps in refining the quality products and enables one to assess the level of drug in a number of species efficiently.
The discovery of a drug and its successful development isn’t a one step process. It is comprehensive cycle that follows multiple steps with each requiring both intellectual minds and high technology. It is estimated that a drug development costs around 1 billion dollars. Plus it requires almost 10 years for a newly discovered formula to reach the market. Just imagine all this money and time going waste because the drug couldn’t work up to the required level. Bioanalytical laboratories reduce the risks of such mishaps to a significant level. Bioanalysis helps to evaluate the properties of a drug at early stages like before it enters clinical phase trials. It ensures that the drug, when enters the market, is safe and efficacious enough and worth all the money and time invested into it.
A number of pharmaceutical companies prefer outsourcing to meet their bioanalytical needs. They look for collaborators who could help them with Bioanalytical services. Olygobio is a well-known name in this regard. They have a notable experience in developing biological products like vaccines and biomarkers. They claim to have experienced scientists for development of bioanalytical methods. Also they guarantee accurate, high-quality results in time. If you are looking for trustworthy Bioanalytical laboratory services for your company, olygobio can be a suitable option.